藉尿素和脂肪酸生成Urea-Clathrate結晶分離正脂肪酸之研究

作者:毛光興

摘要：

本實驗之目的，為研究分離脂肪酸的方法，實驗方法包括含碳數目不同的正脂肪酸（normal fatty acids），在飽和的尿素甲醇溶液中，藉尿素和脂肪酸生成 Urea-Clathrate 結晶，用過濾的方法將結晶和甲醇分離，將結晶容於水中，當 Urea-Clath-rate 結晶確已分解，再藉石油醚正拾碳烷或二硫化碳等溶劑將脂肪酸抽出收回。

《詳全文》

Investigation on the Separation of Normal Fatty Acids by the Formation of Urea-Clathrate Crystal

Author: Kuang Hsin Mao

Abstract：

The separation of normal fatty acids from natural oils has been achieved by a simple and efficient method. Fatty acids with differ-ent number of carbon atoms were first obtained from natural oils or other samples by standard procedures. To a 10 percent solution of such fatty acids urea was added at the rate of 10g per 50ml. Af-ter the urea was brought into solution with heat, the reaction mixture was maintained with shaking at 50-60° C for 30 minutes or longer crystals of urea clathrate (an inclusion complex formed between urea an normal fatty acids), which appeared upon cooling, were fil-tered and the solids in the flter paper washed twice with cold methanol saturated with urea. The crystel, after drying, were dis-solved in water (or weak acid) and the normal fatty acids extract-ed with octane